Grayson County is a county located in the southwestern part of the Commonwealth of Virginia. As of the 2020 census, the population was 15,333. Its county seat is Independence. Mount Rogers, the state's highest peak at 5,729 feet, is in Grayson County.

Cities: Independence, Fries, Troutdale
County seat: Independence
Area: 446 mi²
Population: 15,343 (2022)
Congressional district: 9th
Founded: 1793
Named for: William Grayson